Action potential of cardiac muscle pdf

munication between cardiac muscle cells, the sarcolemma of cardiac muscle is specialized to contain gap junctions (p. ), electrical synapses that couple neighboring cells (Fig. ). When an action potential is initiated in one cell, current flows through the gap junctions and depolar-izes neighboring cells. If depolarization causes the mem-. • The cardiac contractile cell relies on the autorhythmic cell to generate an action potential and pass the impulse down the line before the cell can contract. • Like the autorhythmic cell, it has protein transport channels, but they are slightly different. Cardiac action potentials differ from the APs found in other areas of the body. Typical neural AP duration is around 1ms and those of skeletal muscle are roughly ms, whereas cardiac action potentials range from ms. Nervous and muscle cells (as well as non-pacemaker cardiac cells) use the opening of Na channels to facilitate the depolarisation phase, whereas cardiac pacemaker cells. Action potential of cardiac muscle pdf• The cardiac contractile cell relies on the autorhythmic cell to generate an action potential and pass the impulse down the line before the cell can contract. • Like the autorhythmic cell, it has protein transport channels, but they are slightly different. 2- Describe the cardiac muscle action potential. 3- Point out the functional importance of the action potential (the cardiac muscle action potential is too long compared with the skeletal muscle and also the absolute refractory period is much longer in the cardiac muscle that’s why the cardiac muscle File Size: 2MB. munication between cardiac muscle cells, the sarcolemma of cardiac muscle is specialized to contain gap junctions (p. ), electrical synapses that couple neighboring cells (Fig. ). When an action potential is initiated in one cell, current flows through the gap junctions and depolar-izes neighboring cells. If depolarization causes the mem-. 1 Muscle Contraction: cardiac, smooth and skeletal 1. Types On the basis of structure, contractile properties and control mechanisms, three types of muscle can be identified: 1) skeletal muscle, 2) smooth muscle and 3) cardiac muscle. Although there are significant differences between these muscle types, the force-generating mechanisms are similar. Types of cardiac muscle action potential Fast response Slow response atria, ventricles, His–Purkinje network SAN and AVN a high resting K +permeability between APs. have a low K permeability between APs and are automatic APs generated by fast Na+current APs is generated by Ca+2 current Plateu lack of a well-defined plateau Stable RMP.calated discs distally, towards the working ventricular myocardium. Apart from high glycogen content, one notable feature that marks. out distal. The ionic basis for the cardiac action potential has features which are similar to those of nerve and skeletal muscle (Katz, ), but there are important differences. Studies concerned with atrial or ventricular muscle point towards a similar ionic mechanism for the upstroke of the action potential (DSl~ze, ; Hoffman and. Cardiac muscles are rich in mitochondria because the heart is always contracted (needs ATP), low nuclei. Action potential in the skeletal muscles. Physiology of cardiac myocytes. RESPONSE IN ACTION POTENTIAL Atrial and ventricular muscle, His-Purkinje fibres action potentials. - if you are looking

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